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Studies have shown that silencing CBS notably inhibits OC cell proliferation and metastasis, and increases sensitivity to cisplatin

PMID: 37820623, PMCID: PMC10587873, DOI: 10.1088/1758-5090/ad0261

Its sulfur-containing structure makes it one of few amino acids capable of supporting the broad range of sulfur-dependent pathways and processes in the body

Microspheres demonstrate an increased binding capability compared to the homogenates

For example, in order to maintain intracellular redox homeostasis and build a powerful antioxidant defense, cancer cells are typically characterized by high level of antioxidants, especially GSH with a high concentration of 10 mM, which is approximately ten times higher than that in normal cells (Forman et al., 2009)