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White et al

Miguel Navarro-Alarcn, Carmen Cabrera-Vique - Selenium in food and the human body: a review - Sci Total Environ - 2008 Aug 1 - 400(1-3) : 115-41

In addition to the Leu198Leu genotype in the GPx1 gene, the Ala16Ala genotype in the manganese superoxide dismutase ( MnSOD ) gene, the most significant enzyme that protects against ROS in the human body [90], was also associated with an increased risk of breast cancer [91]

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