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Patients with jaundice, particularly those with hepatocellular DILI, who are at a higher risk of progressing to acute liver failure, typically need close monitoring and are likely to be hospitalized [129]

Liver Detoxification Support Glutathione is a primary hepatic detoxification molecule IV therapy supports liver function and systemic toxin clearance

CHAC1 exacerbates arsenite cytotoxicity by lowering intracellular glutathione levels

The most common adverse effects from the SURMOUNT trials include: Nausea: 24-33% of participants (dose-dependent) Diarrhea: 18-25% of participants Constipation: 13-17% of participants Vomiting: 8-12% of participants Decreased appetite: 10-15% of participants Most of these effects are mild to moderate and occur primarily during dose escalation periods

The evolving role of investigative toxicology in the pharmaceutical industry