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Jaiswal, M

Living in Jaipur means constant exposure to intense UV radiation, desert air, and seasonal dust storms all of which accelerate melanin production and lead to tanning, dark patches, and a dull complexion over time

Intranasal administration leverages the highly vascularised nasal mucosa for systemic absorption

While cytosolic and blood GSH and Cys biochemical species all experience depletion, the model predicts that a single exposure to doxorubicin only results in a minimal perturbation of the antioxidant defence system

Acknowledgements This work was partly supported by Associazione Italiana Ricerca sul Cancro (AIRC) (IG2014-15197 to L.F.) and by grants from the University of Chieti-Pescara G