2017 study reported improvements in aged mice that were sustained through the observation period, suggesting that senescent cell clearance produces durable benefits once senescent cells are eliminated, their pro-inflammatory SASP burden is removed, allowing tissue recovery that persists beyond the treatment window
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We then measured the effect of BPC 157 on nitric oxide production in vascular endothelial cells and examined the role of nitric oxide in BPC 157-induced cell migration