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For example, derivatives of the B vitamins thiamine, riboflavin, niacin, pantothenic, and lipoic acid are also crucial for acetyl Coenzyme A supply to the tricarboxylic acid cycle [141] as cofactors for the enzyme pyruvate dehydrogenase, a pyruvate dehydrogenase complex [142]

The interaction between the SPH domain of HGF and c-MET has been well characterized by X-ray crystallography, showing HGF-SPH makes close contact with the bottom surface of c-MET-SEMA 14

Ferroptosis is defined as iron-dependent regulated necrosis-like cell death caused by membrane damage, which is mediated by a large amount of lipid peroxidation

Ethics statement The studies involving human participants were reviewed and approved by IRB-20220254-R