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This alkylation of proteins involved in parasite redox homeostasis disrupts crucial parasite redox processes, contributing to the artemisinin mechanism of action 4

Lowering the dosage or splitting it into smaller doses throughout the day may help alleviate these symptoms

Results - No significant differences were found between the study and control groups

The formulation process introduces variables that affect how much active peptide actually reaches the dermal target tissue

The rate constant for the fusion construct with dithiol PfGrx C88S was about three times smaller and decreased again fivefold for monothiol PfGrx C32S/C88S (Fig