Although not inherently toxic, extended treatment with ASMswhich is common for patients suffering from a chronic disease like epilepsycan lead to the production and accumulation of toxic secondary metabolites inside the cells, leading to side effects like allergic reactions, cell death and organ damage in severe cases 6
Jr WR, Frankel SR, Jr MW, Scheinberg DA, Itri LM, Hittelman WN, Vyas R, Andreeff M , Tafuri A, Jakubowski A, et al
Fibroblasts are considered to play an important role in skin rejuvenation
Benefit statements have not been evaluated by the FDA.
Additionally, efforts to enhance intrinsic neuronal protective mechanisms, through upregulation of neurotrophic factors, restoration of calcium homeostasis, or stabilization of synaptic plasticity, offer further promise [29, 30]