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This could be due to racial differences in B12 metabolism, or in environmental factors, most obviously diet (B12 intake)

This potential action appears linked to VEGFR2-related pathways, which are involved in nitric oxide signaling and endothelial cell activity

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2-17b), which can alter the electron distribution on a second molecule by repelling or attracting nearby electrons

Belogolova E, Bauer B, Pompaiah M, Asakura H, Brinkman V, Ertl C, Bartfeld S, Nechitaylo TY, Haas R, Machuy N, Salama N, Churin Y, Meyer TF (2013) Helicobacter pylori outer membrane protein HopQ identified as a novel T4SS-associated virulence factor