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This may include mitigating chemical stress, inflammation, DNA damage, and failing mitochondria

For example, one early protocol for substance use disorders employed 500-1,000 mg of NAD+ per day delivered by slow intravenous infusion over several consecutive days

Sun J, Lu Z, Deng Y, Wang W, He Q, Yan W, et al

In addition, maintaining healthy glutathione levels is vital for liver detoxification, which helps break down and remove toxins from the body

Compared with cystine, GSH is highly abundant in the microenvironment of tumours, and supplementation with GSH or its product cysteinylglycine rescues cancer cell growth in cystine-depleted conditions