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(PubMed) Agnew-Blais JC, Wassertheil-Smoller S, Kang JH, et al

Neuroprotective effects of acetyl-l-carnitine (ALC) in a chronic MPTP-induced Parkinsons disease mouse model: endothelial and microglial effects

Orphan Drugs 7 (4), 181197

Endocrinology 143(11):42274234

In summary, our results suggest that CR-mediated metabolic reprogramming suppresses multiple host tumor surveillance prevention mechanics including cell-autonomous immunity and activates signaling pathways of pro-oncogenes, tissue-specific cycling and silenced stem cells, and cancer predisposition genes driving pre-malignant and cancer states