Additionally, cystine/cysteine can regulate GPX4 protein synthesis by activating the Rag-mTORC1-4EBPs signaling axis in a GSH-independent manner, thereby preventing ferroptosis [45]
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3.4 Therapeutic controversies over use of vitamin D supplement during cancer treatment Vitamin D can prevent oxidative and cellular damage, which can reduce the detrimental effects of chemotherapy and radiotherapy
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