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Lofwall, M.R., Walsh, S.L

This direction is particularly relevant to the field of sports medicine, where exercise-induced metabolic adaptations could potentiate the hepatoprotective effects of plant-derived compounds

Our data demonstrate that the adaptive metabolic response to 5FU is mediated through the inhibition of TS function, as we recapitulate these phenotypes by genetic silencing or targeted inhibition of TS using antifolates

Free Radic Biol Med 27:11141121 Martin C, Dubouchaud H, Mosoni L, Chardigny JM, Oudot A, Fontaine E, Vergely C, Keriel C, Rochette L, Leverve X, Demaison L (2007) Abnormalities of mitochondrial functioning can partly explain the metabolic disorders encountered in sarcopenic gastrocnemius