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Rat S9 fractions, which are commonly utilised in the Ames test to assess mutagenicity, may be limited in the detection of genotoxic metabolites from aromatic amides due to their poor concordance with human in vivo amide hydrolysis

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HGF Dimerization HGF dimerization was assessed using PAGE followed by silver staining (Kawas et al., 201 1 ), Human HGF at a concentration of O.OSng/ with or without 6-AH analogs was incubated with heparin at a final concentration of 5 g/ml