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See Sikiric et al., Curr Pharm Des, 2018 (PMID:30246642) for an overview of the reported mechanisms, and Chang et al., J Appl Physiol, 2011 (PMID:21030673) for a representative tendon-fibroblast study

This is a common reaction to the medications stimulant effects

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Conclusion While Vitamin B12 injections are effective in treating deficiencies and related conditions, they can cause a range of side effects, from mild skin reactions to severe anaphylaxis and neurological symptoms

This makes the arginate version significantly more stable in liquid and across various pH levels, especially in the acidic environment of the stomach