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Stroke-induced chronic systolic dysfunction driven by sympathetic overactivity

The Microbiome and Rheumatoid Arthritis: The gut microbiome is made up of over 1000 different species of microbes, and it plays a huge role in nutrient absorption, detoxification, and the development and maturation of the immune system

Communication between the gastrointestinal tract and the brain is facilitated by the gutbrain axis, which includes the central nervous system, spinal cord, enteric nervous system, autonomic nervous system, and hypothalamic-pituitary-adrenal (HPA) axis [151]

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These benefits have been consistently confirmed in subsequent clinical trials and meta-analyses, leading to iSGLT2 being recognized as a first-line treatment for diabetic patients with elevated cardiovascular risk and HF 12,13,14,15