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The pharmacological inhibition of ABCC induced a proliferation increase induced by mitogen of lymphocytes obtained from HTLV-1-infected individuals [19]

Similar results were obtained in vivo with enhanced reduction of patient xenograft tumor volume and the number of cells positive for proliferation markers

Siener R, Jansen B, Watzer B, Hesse A

Notably, RT-qPCR analysis showed a sharp increase in OCT4 mRNA expression, a marker of pluripotent stem cells and essential for TIC self-renewal [33], in the colonies formed in 3D gels relative to 2D culture conditions (Fig

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