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On the other hand, overexpression of cardiomyocyte PGC1 also causes cardiac dysfunction (14)

These include improved energy and vitality that enhance daily productivity and life enjoyment, better recovery from illness or physical exertion, potential long-term health benefits from optimal antioxidant status including disease prevention and healthy aging, skin appearance improvements that enhance confidence and self-perception, and overall sense of wellbeing and health optimization

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Importantly, the underlying cell death mechanism is triggered by CBS inhibition in HepG2 cells via ferroptosis, suggesting that CBS has a previously unreported function in this process