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3,417 adults randomized to cagrilintide 2.4 mg + semaglutide 2.4 mg, cagrilintide alone, semaglutide alone, or placebo for 68 weeks

This double layer of epithelium is composed of a pigmented epithelium (PE), which interfaces with the highly vascularized stromal tissue that contains fenestrated capillaries, and a non-pigmented epithelium (NPE) which interfaces with the aqueous humor [73]

This isn't an immediate switch-off but more of a slow adjustment back to how things were, meaning any improvements in skin texture and firmness gained during use might lessen over time

Participants receiving 1 mg per day of AOD 9604 lost approximately 2.6 kg compared to 0.8 kg in the placebo group

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