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Co-therapies and drugs that preserve lean-mass, prevent excessive lean-mass loss or that promote loss of fat- over lean- mass may also find a sizeable market

Where GLP-1 primarily activates hypothalamic neurons involved in energy balance, amylin targets hindbrain circuits that regulate meal-specific satiety and food reward

Cathepsin L regulates oocyte meiosis and preimplantation embryo development

Kageyama and Suda, 1 receptors are also upregulated in rodents exposed to acute or chronic stress by a CRF feed-forward mechanism (Bonaz and Rivest, 2014

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