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400 Conditional activation of autophagy under stress-responsive conditions is another emerging approach

Le Roith D, Bondy C, Yakar S, Liu J-L, Butler A

Indeed, NF-B triggers a cascade of molecular events, some of which may be potential key targets for the treatment of inflammation, and melatonin performs part of its anti-inflammatory functions by modulating nuclear NF-B translocation 73,78,79

Moreover, glial cells such as microglia and astrocytes play a dual role in buffering iron: while they can sequester iron released from dying neurons, their own ferroptosis may exacerbate inflammation and oxidative stress

Mohammadi EN, Louwies T, Pietra C, Northrup SR, Meerveld BG-V