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[140] One cohort study found that melatonin use was associated with a decreased risk of developing age-related macular degeneration (AMD) and a slower progression from nonexudative to exudative AMD, supporting further research into melatonin's potential as a preventive therapy for AMD

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A 2022 systematic review in Growth Hormone & IGF Research identified 47 clinical trials involving Tesamorelin versus 23 for Sermorelin reflecting the significantly higher clinical investment in Tesamorelins metabolic applications

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