The pups exposed to cytarabine showed a significant and dose-dependent (a) decrease in body weight, liver weight, hepatosomatic index, catalase, superoxide dismutase, glutathione, glutathione peroxidase, serum albumin levels and (b) increase in malondialdehyde, alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase, AST/ALT ratio, and histopathological anomalies
Do not take high doses or exceed the recommended amount, as high doses of antioxidants may have adverse effects
Future research will explore if Tyr-NO 2 may be an alternative marker for C-reactive protein (CRP) a well-established marker of acute inflammation, synthesized by upregulated inflammatory cytokines in the liver (Baumgartner et al
Second is the role of PA in attenuating oxidative stress, which in turn may lead to increased SIRT-1 expression ( SIRT-1 upregulation (Zhang and Tang, 2023)
These medications, along with numerous other over-the-counter and prescription drugs, can impede the bodys ability to digest, absorb, synthesize, or utilize specific nutrients