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In addition, while we effectively achieved intestine-specific TXNIP overexpression via plasmid-mediated delivery, long-term effects were not evaluated

Colvin OM, Friedman HS, Gamcsik MP, Fenselau C, Hilton J

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Applying intracellular lactate to isolated pyramidal and subthalamic nucleus neurons resulted in depolarization, while inhibiting lactate conversion in astrocytes caused hyperpolarization in the same neurons [104]

GPR43, G protein-coupled receptor 43