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Both types are used based on whats best for each patient

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In the STEP 4 trial, participants who stopped semaglutide regained about two-thirds of the weight they had lost within one year (STEP 4 withdrawal study)

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In lieu of within-participant differences that inherently exist in all studies with humans, this result may have been due to issues with effort exerted during the resistance training sessions, perhaps related to over-reaching and fatigue, differences in resistance training volume, supplementation compliance, and differences in dietary intake