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Heavy alcohol use should be avoided, as it increases the risk of pancreatitis, a rare but serious side effect of tirzepatide

The exception is when using very high, advanced doses of metabolic peptides, where a larger individual may need the upper end of the range

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Intestinal bacteria: Thyroid disease and intestinal disease commonly coexist, probably because of disruption of the intestinal barrier, where it is easier for antigens to pass through and react with the immune system or with extra-intestinal tissues to intersect and destroy thyroid cells