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Consequently, there is an increasing need for other methods to combat PD, such as lifestyle modifications to prevent the disease and slow its progression in those who have already developed it [12]

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Repeated seizures can cause oxidative stress, inflammation, and excitotoxic damage and eventually lead to neuronal death, including apoptosis, autophagy, necrotizing apoptosis, scorch death, and iron death (10, 11)

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In the absence of GPx4 activity, lipid peroxides accumulate within cellular membranes

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Sundaravalli et al., 1982

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