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I've used up ampoules that are long out of date and have been subjected to fluctuating heat (terrible for wine!) due to being in my car, etc, and haven't noticed any difference

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Another supplement is especially suitable for athletes, regardless of gender

After 48 weeks, 36%-48% of subjects receiving 8 mg and 12 mg doses achieved 25% weight reduction, with no participants in the placebo group reaching this level