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This ability to visualize a physical entity, even imperfectly, is a significant advance over the previous invisibility of unresolved structures in electron density maps: a fuzzy image of an IDP/IDR is still more informative than having no structural data at all

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Many diseases, such as cancers, cardiovascular diseases, neurodegenerative diseases, metabolic disorders, liver diseases, autoimmune diseases, and ocular diseases, are closely associated with mitochondrial dysfunction (Fig

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