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Neuropsychopharmacol 33 , 21872199 (2008)

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Interestingly, core clock genes can affect circadian rhythmicity and composition of the gut microbiota, with studies in Bmal1 - (56) and Per1/2 -deficient mice (57) reporting abolishment of diurnal microbial oscillations and a shift toward a more proinflammatory gut microbiota profile

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Too often, advice on combating this condition is fragmented, leaving individuals to piece together conflicting information about diet, exercise, and supplements