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K-ras mutation may promote carcinogenesis of endometriosis leading to ovarian clear cell carcinoma

Halliwell, B., Hoult, J

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During tumorigenesis, a pre-existing chronic inflammatory conditions elicit higher level of immune inhibitory cytokines and other immunosuppressive factors

Regarding the expression distribution of core ferroptosis-suppressing genes, GPX4 ( Figure 7C ), a critical ferroptosis inhibitor, exhibits significantly altered expression patterns in AKD and CKD compared to normal kidneys, suggesting potential remodeling of its ferroptosis-suppressive function during renal injury