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Hong D, Lunagomez S, Kim EE, Lee JH, Bresalier RS, Swisher SG , Wu TT, Morris J, Liao Z, Komaki R, Ajani JA
In Alzheimer's disease (AD), there is an aberrant activation of inflammasomes, molecular platforms that drive inflammation through caspase-1-mediated proteolytic cleavage of proinflammatory cytokines and gasdermin D (GSDMD), the executor of pyroptosis
doi: 10.4049/jimmunol.1000866 197 MahajanSDkharHKChandraVDaveSNanduriRJanmejaAKet al
Key Points Animal studies suggest that BPC-157 offers widespread healing benefits across the body, including: Accelerated healing and functional recovery of tendons, ligaments, muscles, and bones Support for wound healing through key regenerative processes Reversal of corticosteroid-induced damage Protection and therapeutic effects on gut health, including inflammatory conditions and ulcers Nerve regeneration and neuroprotection against spinal cord injury, brain trauma, and neurotoxicity Improvements in motor function, learning, mood regulation, and neurodegenerative conditions Tendon, Ligament, and Muscle Repair BPC-157 has accelerated the healing of various tissues, including tendons, ligaments, muscles, and bone in numerous preclinical studies
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