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Inefficient intracellular methylations may lead to the chronic damage of numerous proteins, which might in turn be involved in atherothrombogenesis

In aged mouse cohorts, long-term administration was associated with reduced incidence of spontaneous tumours

Sulfur-rich foods Sulfur is a chemical element found in many amino acids, including those needed to produce glutathione

So in ALS, rather than driving pathology, the baseline microbiome might be trying to counteract it, and losing key microbes removes that brake on microglial activation