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PMC Franklin CC, et al

Reaction mechanism of glutathione synthetase from Arabidopsis thaliana : site-directed mutagenesis of active site residues

Dietary modifications : Adjusting the intake of sulfur-containing foods and considering the balance of different sulfur compounds in the diet

DEFINITION Glutathione reductase, also known as GSR or GR, is an enzyme (EC 1.8.1.7) that reduces glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant

These findings align with previous reports that melatonin reduces ILC2-derived IL-5 and IL-13 in oxazolone-induced colitis models (65), suggesting a conserved anti-inflammatory effect of melatonin across tissues