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Hypoxia sensing by hepatic stellate cells leads to VEGF-dependent angiogenesis and may contribute to accelerated liver regeneration

SLC7A11 represents a master upstream regulator of GSH synthesis and ferroptosis suppression 136

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This suggests that the higher rates of glucuronidation associated with this UGT1 polymorphism protect against paracetamol hepatotoxicity by decreasing the fractional proportion of paracetamol available for oxidation

The mobile phase consisted of 0.1% formic acid in water (A) and methanol (B), with a gradient elution: 2% B to 30% B over 30 min, then to 60% B in 8 min, to 100% B in 2 min (hold 5 min), and re-equilibration to initial conditions in 1 min