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which are similar to CQ (0.191)

250 In fact, this modest selectivity of Ec ZntR has been exploited in the selection of engineered ZntR mutants capable of detecting xenobiotics 329,333,334 that are subsequently leveraged in the design of whole cell biosensors (Section 3.4)

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This would decrease circulating levels of estrogen, gonadotropin-releasing hormone (GnRH), prolactin, and gonadotropins and the ability of melatonin to modulate the activity of enzymes involved in the synthesis of estrogens, both gonadal and extragonadal