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Oxidative stress responses clarified the functioning of central principal switches like nuclear factor (NF)-B (NFB) or the Kelch-like ECH-associated protein 1 (Keap1)-Nuclear factor erythroid 2-related factor2 (Nrf2)-antioxidant response element (ARE) redox regulator pathway (Sies, 2015

We base this suggestion on the modelled position of Arg 130 in the MGST1-TNB-Meisenheimer complex, suitable for stabilizing the delocalized negative charge of the charge transfer complex

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Emanuele et al., 2021)

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