As with any research compound, careful protocol design, observation, and adherence to ethical guidelines are paramount
Room temperature storage (up to 77 degrees Fahrenheit / 25 degrees Celsius) is acceptable for short periods, such as during shipping, but shouldn't be the long-term approach
Classified as a highly advanced, synthetic small molecule inhibitor, this specialized compound is masterfully engineered to target and block the activity of a specific metabolic enzyme known as NNMT (nicotinamide N-methyltransferase)
These reactions are primarily mediated by UDP-glucuronosyltransferases (UGTs) and sulfotransferases (SULTs), which generate major circulating metabolites such as luteolin-7-O-glucuronide and luteolin-3-O-glucuronide (Xiong et al., 2023)
instead, they decrease neuronal survival