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Only GSH treated plants G1, G2 and G3 showed 1.7 fold, twofold and 1.7 fold increase, respectively as that of control

However, several studies in both animal models 14 and humans, 15 have shown no benefit on either activity, or even on muscle LC content in normal individuals

This limited its use in large-scale compounding pharmacies

GSH is a tripeptide composed of three amino acids (cysteine, glutamate, and glycine), which exists in a reduced (GSH) or an oxidized state (GSSG)

Nanocarriers such as AZOSH or IS@ATF enable triggered or targeted NO release, leading to GSH depletion, ONOO generation, and significant tumor weight reduction in murine models (36, 126, 127)