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In the B16-OVA murine melanoma model, a single vaccination with OVA mRNA-LNPs was shown to significantly increase survival compared to a control group injected with PBS

By overcoming key delivery limitations, EGT presents a promising therapeutic strategy for oxidative stress-related ocular diseases such as age-related macular degeneration and diabetic retinopathy

The extent of hepatic damage, along with levels of proinflammatory cytokines, chemokines, and neutrophil infiltration, remains comparable to that observed in wild-type controls

Cell Commun Signal 22(1):7

The consistent finding across this body of work: no evidence of carcinogenic potential