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In some embodiments, an otic composition or formulation disclosed herein comprises less than about 50 ppm of water

DSIP is ideal for individuals experiencing insufficient deep sleep despite adequate total sleep time, difficulty falling asleep or maintaining sleep, poor sleep quality affecting daytime function, recovery challenges in athletic or high-performance contexts, circadian rhythm disruption from travel or shift work, or age-related sleep quality decline

For example, if a vial contains a known total amount of peptide and it is reconstituted with 2 mL of bacteriostatic water, then dividing the total by 2 gives the concentration per mL

Rubinstein, Jeremy D

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