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This project was funded by start-up funds from Washington State University, Vancouver to A

In mice, administration of MOTS-c improved markers of endothelial performance, suggesting that it can enhance vascular reactivity and health

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Beyond the regulatory picture, online forums and peptide communities frequently raise a structural argument about why human trials may never happen: BPC-157s amino acid sequence is in the public domain, which would make it difficult to patent and therefore commercially unattractive for a pharmaceutical company to fund through the expensive late-stage trial process

TrkB signaling carries context-dependent risks, including altered seizure susceptibility, which makes human translation a careful process