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Smith and David M

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Circulation 24 , 788796 (1961)

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The dosing calculations below will help you translate these ranges into specific injection volumes based on your vial size and reconstitution method

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At maintenance doses of 8 to 12mg, the wearing-off effect is much less pronounced

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This shift in energy metabolism is consistent with mitochondrial impairment, which forces cells to rely more heavily on glycolysis, producing lactate as a by-product

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