Potent antioxidant that can help protect cells from damage caused by free radicals
It has demonstrated a strong safety profile and is currently used for non-therapeutic experimental applications only
Hypogonadism is considered as the most important clinical feature of LOH a term coined in 2002 and specified by the International Society of Andrology (ISA), International Society for the Study of the Aging Male (ISSAM), European Urology (EAU), European Academy of Andrology (EAA), and American Society of Andrology (ASA) [64]
Gastroprotection Gastric mucosa Protection and healing of gastric ulcers, colitis, and intestinal lesions in animal models
In melanoma, downregulation of IGF-1 reduces the dry character of melanoma initiating cells, including the expression of dry markers (SOX2, Oct-3/4, CD24 and CD133) and functional properties (melanosphere formation, aldehyde dehydrogenase activity and side population) and eventually inhibiting the proliferation and metastasis of tumor cells (26)