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132 Dehydrocostus lactone exerts different pharmacological benefits, including pro-apoptotic, 133 anti-proliferative, 134 anti-fibrotic, 135 and anti-inflammatory

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Results Cisp administration (8 mg/kg, IP) significantly impaired liver function, increased oxidative stress, promoted apoptosis (increased BAX, CASPASE-3, and decreased BCL2) and disrupted homeostasis by increasing the ferroptosis upstream ferritinophagy (decreased ferritin and increased NCOA4)

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