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In this way, the asparagine residue creates a negative redox potential within the active site, which is required for the catalytic reaction, as the imidazolate strengthens the metal-histidine bond, which in turn stabilizes the metal in its higher/highest oxidation state

For instance, certain antibiotics and vaccines require dilution with sterile water to form injectable solutions

Glutamine concentrations across the three voxels were significantly correlated with each other

After silencing GPX4 expression, knockdown of iPLA2 enhanced the sensitivity of cells to ferroptosis

d , Immunofluorescence analysis of indicated proteins in HeLa cells treated with vehicle or BSO (1 mM) for 24 h