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The enzymes carnitine-palmitoyl-transferase-1 (CPT I), CPT II and carnitine-acylcarnitine translocase (CACT) are essential in catalyzing these reactions (Figure 2)

doi: 10.1038/s41556-025-01790-y

HIF-1-deficiency results in dysregulated EPO signaling and iron homeostasis in mouse development

For the first time, an FGF21 analog induced a strong reduction in liver fat that appeared to be associated with resolution of histological features of NASH, including fibrosis (298)