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C.McLendonC.ShojiM.KawarabayashiT.et al (2002)

As a consequence, the main mitochondrial proteome (~1500 proteins) is encoded by the nucleus, translated in the cytosol and imported into the mitochondria through specific translocator complexes (TIM and TOM) of the inner mitochondrial membrane (IMM) and outer mitochondrial membrane (OMM), respectively

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According to the American Academy of Sleep Medicine, lack of sleep speeds up biological aging since it boosts the molecular process involved in growing older

Numerous additional questions remain regarding the catabolism of metabolites and their impact on tissue homeostasis in disease