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Ongoing trials targeting this population reflect how suitable it is

Neuron 89 , 11311156 (2016)

It binds to toxins, making them soluble and ensuring they can be excreted through urine or bile

Innate Repair Receptor (IRR) Activation: ARA-290 binds selectively to the IRR (EPOR/CR heteromer), activating the full IRR-mediated tissue protection cascade: JAK2/STAT3, PI3K/Akt, and MAPK/ERK signalling, producing anti-apoptotic, anti-inflammatory, and regenerative downstream effects across neural, vascular, and metabolic cell types