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Occasional reports mention mild gastrointestinal effects including nausea or changes in appetite

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Gallbladder events rise modestly, especially with rapid loss. Less common signals include skin dysesthesia, which is now on the label, and a small thyroid-cancer association in two population studies with a tiny absolute event rate. Depression and suicidality remain unproven

The difference in cagrilintide doses used between the two studies was based on the available evidence at the time the studies were planned

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